Augmentation of osteochondral repair with hyperbaric oxygenation: a rabbit study

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Augmentation of osteochondral repair with hyperbaric oxygenation: a rabbit study

BACKGROUND Current treatments for osteochondral injuries often result in suboptimal healing. We hypothesized that the combination of hyperbaric oxygen (HBO) and fibrin would be superior to either method alone in treating full-thickness osteochondral defects. METHODS Osteochondral repair was evaluated in 4 treatment groups (control, fibrin, HBO, and HBO+fibrin groups) at 2-12 weeks after surgi...

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Hyperbaric Oxygenation permits a controlled increase of the partial oxygen pressure in the blood. This technique can be used in cases of tinnitus and sudden deafness when the development in the inner ear and the brain lead to a lack of oxygen and so to a limited energy provision. The results to date allow the recommendation to apply an oxygen high pressure therapy when standard treatments have ...

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Peripheral nerves are essential connections between the central nervous system and muscles, autonomic structures and sensory organs. Their injury is one of the major causes for severe and longstanding impairment in limb function. Acute peripheral nerve lesion has an important inflammatory component and is considered as ischemia-reperfusion (IR) injury. Surgical repair has been the standard of c...

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ژورنال

عنوان ژورنال: Journal of Orthopaedic Surgery and Research

سال: 2010

ISSN: 1749-799X

DOI: 10.1186/1749-799x-5-91